Production Process

 

Mother Tincture

 

 

Homoeopathic mother tinctures are prepared from the following kingdoms:

 

  • Vegetables
  • Minerals
  • Animals
  • Imponderablias
  • Nosodes

 

Preparations:

 

  • Dr. Hahnemann have directed, how to prepare mother tinctures, in his work “ Materia Medica Pura”
  • Alcohol or distilled water, is used to prepare the mother tincture or mother solutions
  • Under the Hahnemannian guidelines, Mother tinctures are prepared for treatment purposes

 

 

 

Production Process:

 

 

 

Our company holds specialization in offering Mother Tinctures Homeopathic Medicines for sale. In homeopathy science, the medicines that are soluble in water/alcohol are first prepared in Mother Tincture Form. Mother Tincture is the extract obtained from the original drug substance; this extract is being made with water or ethyl alcohol in certain proportion (According to HPI, HPUS, BHP). The original drug substances are macerated in a mixture of water or alcohol, in pharma grade stainless steel containers. After completion of maceration/ percolation, it is subjected to hydraulic press for separation of tincture to optimum level from the residual herbs. The tincture so obtained is further filtered to obtained clear solution (tincture). Further, the potencies are prepared from Homeopathic Mother Tinctures. Over the years, we have been able to establish ourselves as the leading Manufacturer and Supplier in this challenging field of work. All the processes undertake by us are conducted with utmost precision & under expert supervision so as to make sure that there is no scope for any flaw.

 

 

 

Bio-Chemic

 

Production Process:

 

The Tissue Remedies (Bio-Chemic) are prepared for therapeutic purposes, like all homeopathic remedies, according to the decimal scale in trituration. The crude, chemically pure article is taken and triturated with sugar of milk, one part of the drug to nine parts of sugar of milk, for at least one hour (According to HPI, BHP). This gives the first decimal trituration, each grain containing one-tenth of a grain of the cell salt triturated.

 

One part of this first decimal trituration is then used, and other nine parts of sugar of milk added and again triturated one hour, which gives the second decimal trituration. In homeopathy, a trituration that is more triturate is described as having a higher potency, and more triturate substances are considered by homeopaths to be stronger and deeper-acting remedies. So this triturating process has been kept up to the sixth, twelfth and even higher preparations.

 

 

Dilutions

 

Production Process:

 

Mortar and pestle used for grinding insoluble solids, including quartz and oyster shells, into homeopathic remedies.

 

In producing remedies for diseases, homeopaths use a process called "dynamisation" or "potentisation", whereby a substance is diluted with alcohol or distilled water and then vigorously shaken by 10 hard strikes against an elastic body in a process homeopaths call "succussion". Hahnemann advocated using substances that produce symptoms like those of the disease being treated, but found that undiluted doses intensified the symptoms and exacerbated the condition, sometimes causing dangerous toxic reactions. He therefore specified that the substances be diluted, due to his belief that succussion activated the "vital energy" of the diluted substance and made it stronger. To facilitate succussion, Hahnemann had a saddle-maker construct a special wooden striking board covered in leather on one side and stuffed with horsehair. Insoluble solids, such as quartz and oyster shell, are diluted by grinding them with lactose ("trituration").

 

Three logarithmic potency scales are in regular use in homeopathy. Hahnemann created the "centesimal" or "C scale", diluting a substance by a factor of 100 at each stage. The centesimal scale was favored by Hahnemann for most of his life. A 2C dilution requires a substance to be diluted to one part in 100, and then some of that diluted solution diluted by a further factor of 100. This works out to one part of the original substance in 10,000 parts of the solution. A 6C dilution repeats this process six times, ending up with the original substance diluted by a factor of 100−6=10−12 (one part in one trillion or 1/1,000,000,000,000). Higher dilutions follow the same pattern. In homeopathy, a solution that is more dilute is described as having a higher potency, and more dilute substances are considered by homeopaths to be stronger and deeper-acting remedies. The end product is often so diluted as to be indistinguishable from the dilutant (pure water, sugar or alcohol). There is also a decimal potency scale (notated as "X" or "D") in which the remedy is diluted by a factor of 10 at each stage.

 

 

 

Production Process (Unani Medicine)

 

Deeplaid follows the galenic manufacturing procedure in it’s Unani production division from the beginning. We are following the Bangladesh Government authorized B.N.U.F (Bangladesh National Unani Formulary) as per govt. rule. We also follow Hamdard Pharmacopoeia of Eastern Medicine, Hamdard Therapeutic Index, Biaz-e-kabir, Kitabul Murakkabat, Karabadin-e-kabir. Here we manufacture four therapeutic types of medicine i.e Liquid (Syrup), Solid (Tablet, Capsule, Powder), Semisolid (Halwa) and ointment as well as.  For our liquid product manufacturing we use herbal extraction plant for our quality effective product. In this plant we use the plant in the following way in a brief.

 

Our Herbal Extraction Plant

 

The Herbal Extraction Plants are meant for extracting the active ingredients that are presents in various natural organic compounds. The process of extraction depends on the solubility of the compounds in that particular extraction media. The process of extraction is however very difficult to generalize. The extraction plant is differently designed for extracting isolated compounds from different herbs. A whole series of processes is involved in extracting isolated compounds from raw material.

CLEANING & BLENDING:


In the first step, the compounds are extracted. In the second step, these compounds are purified and isolated by various physical / chemical processes. These extracted herbal extracts can be used in various formulations for herbal, pharmaceuticals, food and cosmetic industries. Some of the herbal extracts can be used as natural dyes for textile, leather, food and cosmetic applications as coloring matters.

 

We are going to process new unique technology based projects specially developed by some of our team of scientists with rich experience & expertise on the following extracts. :

  • Active Principles from plant materials. (Sennoside, Escin, Polycosanol, Artimisinin, Colchicine)
  • Herbal Nutraceutical (Green tea EGGC, Soya isoflovonoids)
  • Fruit powders Spray dried. (Amla, Citrus, Tomato, Mango)
  • Juice powder Spray dried. (Aloe, sugar cane juice)

 

For the purpose of a Quality Extraction our Plant is divided in to:

  • Extractors

 

  • Evaporators 

 

 

  • Dryers

 

 

  • Filters

           

 

  • Columns

 

 

 

 

Sample: How WE COLLECT INDIAN gOOSEBERRY EXTRACT

 

The extraction process is a multi-stage phenomenon which involves pulverizing, extraction and evaporation. The same process is used for extraction of different kinds of herbs. First the cleaned raw material (herb) is taken .Raw material goes through pulverizer which crushes to give powdered form of the raw material. Solution of that powder is made using solvent which is herb specific. The process of preparation of Indian gooseberry extract is as follows:

 

 

Factors affecting selection of an extraction process

 

Before taking a herbal extract we care the following factors for a best quality of herbal extraction.

  1. Character of Herb:- The knowledge of pharmacognosy of the herb is essential to select the right method of extraction process. The maceration process is used when the herb is soft, unorganized un powder able and to avoid powdering of it. The percolation process is used when the herb is hard and tough.
  2. Therapeutic value of the herb:- When the herb has considerable therapeutic value, the maximum extraction is required, so the percolation process is used e.g. Belladonna. In case the herb has little therapeutic value, the efficiency of extraction is unimportant, and maceration process can be used to extract the herb.
  3. Stability of herb:- Continuous hot extraction process should be avoided when the constituents of the herb are thermo labile in nature; in that case maceration or percolation process may be used to extract the active constituents of the herb.
  4. Solvent:- If water is used as a solvent the maceration process should be recommended. The percolation process should be preferred if non-aqueous solvents are used for extraction.
  5. Concentration of product:- The dilute products such as tinctures can be made by using maceration or percolation process, depending on the other factors. For semi-concentrated preparations, such as concentrated infusions, double or triple maceration process can be used. The liquid extracts or dry extracts which are concentrated preparations are prepared by using percolation process.

 

 

Distillation of Herbs

We also use distillation process for some of our unique liquid product for our loyal consumer home & abroad.

 

 

Distillation, as the most important process for obtaining essential oils, needs attention first. It may be defined as the "separation of the components of a mixture of two or more liquids by virtue of differences in their vapor pressure"

 

(i) Water Distillation

 

When this method is employed, the material to be distilled comes in direct contact with the boiling water. It may float on the water or be completely immersed, depending on its specific gravity. The water is boiled by application of heat by any of the usual methods, i.e., direct fire, steam jacket, closed steam coil, etc. Through this method, powdered materials like almond and others like rose petals and orange blossoms are distilled.

 

 Disadvantages of Water Distillation

 

1. If the temperature is high there will be browning of the essential oil.2. In this method, certain compounds like esters are partly hydrolyzed.3. It requires a greater number of stills, more space and more fuel.4. It demands considerable experience and familiarity to successfully use this method.

 

(ii) Water and Steam Distillation

 

In this case, the plant material is supported on a perforated grid or screen inserted at some distance above the bottom of the still, and the lower part of the still is filled with water to a level below the grid. The water is heated. The typical features of this method are: first, that the steam is always fully saturated, wet and never super-heated; second, that the plant material 'is in contact with the steam only and not with the boiling water. This method gives best results with materials like seeds and roots.

 

 Disadvantages of Water and Steam Distillation

    1. To obtain the best results, it is necessary that the charge should be in homogenous individual pieces.2. If the material is extremely wet, it results in lumping or agglomeration of the charge.3. It takes a comparatively long time for distillation.

 

(iii) Steam Distillation

 

Distillation is the process by which essential oils are extracted from aromatic crops. This can be done in two ways: In this process, steam generated in a boiler is passed through steam pipes into distillation tank which is filled with harvested aromatic crop. Pressure, temperature and amount of the steam can be regulated as per requirement; thereby time of distillation can also be varied. The steam converts the essential oil in the aromatic plants into oil vapor and both these pass through delivery pipe into condenser where due to the effect of circulating cold water, steam and oil vapor condense and the resulting mixture of water and essential oil is collected in the receiver of separator. Since the density of oil is relatively lesser than water, the oil floats on water and can easily be taken out from the separator through the outlet provided specially for taking out oil. This process is used in large scale production of essential oils from aromatic crops. The equipment (boiler, distillation tank, condenser and separator) needed for this process is expensive and needs technical personnel to run the boiler. This distillation unit consists of the following parts.

 

a. Furnace and Chimney

 

The furnace is constructed with bricks and mud and is used for heating the distillation tank kept over it. This can be fired using fire wood or exhausted plant material left after distillation or weeds. The chimney is made of mild steel and is useful for carrying the smoke coming out from furnace.

 

b. Distillation Tank or Retort

 

This is made of mild steel and is either cylindrical or rectangular in shape. The capacity of the tank is fixed based on the requirement. A special mesh fixed in it divides it into two parts and facilitates filling of water below and plant material above the mesh. A fixed number of G.I. pipes are welded at the bottom for increasing fuel efficiency.

 

c. Condenser

 

The outer shell and legs are made of mild steel and the tubes inside the shell are made of aluminum. This is connected to the distillation tank with the help of a delivery pipe. During distillation, cold water circulates in the condenser. The main purpose of the condenser is to condense the mixture of steam and oil vapor into water and essential oil.

 

d. Receiver or Separator

 

This is made of aluminum and is used to collect the mixture of water and oil coming out from the condenser. Separate outlets are provided for overflow of excess water and for taking out essential oil.

 

e. Storage and packing of Essential oil

 

Care is taken to ensure that the essential oil does not contain any water before storage. Amber colored bottles are convenient for small quantities. For large quantities, Steel or aluminum drums are widely used. The oils are left to stand for sometime so that water can settle down. If the oil is still turbid, a small amount of common salt is added and the oil filtered. The containers are filled up to the brim, tightly capped and stored in.

 

 

 

Tablet /Capsule Processing:

 

In this process required amount of herbs are collected from store and then they are weighed and washed, dried and crushed as per S.O.P. Next the powder is mixed with other excipients   and aqua as per formulation and a lump is made. Next the lump is milled with a multimill and sends to the dryer for dry granulation. When the granules are completed those are send to the compression for tablet and encapsulation for capsule preparation as well as.

 

 

  Ointment Processing

 

In this process we at first take active and excipients as per S.O.P. Next sieve the active with a 40 messed screen and sieve them and next put them in a planetary mixing vat. Next add excipients into the active and increase the heat as needed. After a certain standard time the whole solution will be mixed homogenously & then it will be ready for tube filling. Thus we prepare all of our ointments. Especially our Fuci, Ruba And Rec ointment are unique product in Bangladesh. Our competitors are not advance than us in this ointment field.